Clarithromycin is principally excreted by the liver, klacid clarithromycin 125mg/5ml. Therefore, caution should be exercised in administering this antibiotic to patients with impaired hepatic function. Caution should also be exercised when administering clarithromycin to patients with moderate to severe renal impairment.
Klacid of fatal hepatic failure see section 4. Some patients clarithromycin have had pre-existing hepatic disease or may have been taking other hepatotoxic 125mg/5ml products.
Patients should be advised to stop treatment and contact their doctor if signs and symptoms of hepatic disease develop, such as anorexia, klacid clarithromycin 125mg/5ml, jaundice, dark urine, pruritus, or tender abdomen. Pseudomembranous colitis klacid been reported with nearly all antibacterial agents, including macrolides, donepezil attention deficit disorder may range in 125mg/5ml from mild to life-threatening.
Clostridium difficile- associated diarrhoea CDAD has been reported with use of nearly all antibacterial agents including clarithromycin, and may range in severity from mild diarrhoea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon, klacid clarithromycin 125mg/5ml, which may lead clarithromycin overgrowth of C. CDAD must be considered in all patients who present with diarrhoea following antibiotic use.
Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
Therefore, discontinuation of clarithromycin therapy clarithromycin be considered regardless of the indication. Microbial testing should be performed and adequate treatment initiated. Drugs inhibiting peristalsis should be avoided. There have been post-marketing reports of colchicine toxicity with clarithromycin use of clarithromycin and colchicine, especially in the elderly, some of klacid occurred in patients with renal insufficiency.
Deaths have been reported in some such patients see section 4, klacid clarithromycin 125mg/5ml. Concomitant administration of clarithromycin and colchicine is contraindicated see section 4.
Caution is advised regarding concomitant administration of clarithromycin and triazolobenzodiazepines, such as triazolam, and intravenous or oromucosal midazolam see section 4. Prolongation of the QT Interval Prolonged cardiac repolarisation and QT interval, imparting a risk of developing cardiac arrhythmia and torsades de pointes, have been seen in treatment with macrolides including clarithromycin see section 4.
Clarithromycin must not be given to patients with hypokalaemia see section 4. In view of the 125mg/5ml resistance of Streptococcus pneumoniae to macrolides, it is important that sensitivity testing be performed when prescribing clarithromycin for community-acquired pneumonia. In klacid pneumonia, clarithromycin should be used in combination with additional appropriate antibiotics. Skin and soft tissue infections of mild to moderate severity: 125mg/5ml infections are most often caused by Staphylococcus aureus and Streptococcus pyogenes, both of which may be resistant to macrolides.
Therefore, it is important that sensitivity testing be performed.
In cases where beta—lactam antibiotics cannot be used e. Currently, macrolides are only considered to play a role in some skin and soft tissue infections, such as those caused by Corynebacterium minutissimumacne vulgaris, and erysipelas and in situations where penicillin treatment cannot be used.
In klacid event of severe acute hypersensitivity reactions, such as anaphylaxis, Stevens-Johnson Syndrome, toxic epidermal necrolysis, klacid clarithromycin 125mg/5ml, and DRESS, clarithromycin therapy should be discontinued immediately and appropriate treatment should be urgently initiated.
Clarithromycin should be used with caution when administered concurrently with medications that induce the cytochrome CYP3A4 enzyme see section 4, klacid clarithromycin 125mg/5ml. Concomitant use of clarithromycin with lovastatin or simvastatin is contraindicated see section 4.
125mg/5ml should be exercised when prescribing clarithromycin with other statins. Rhabdomyolysis has been reported clarithromycin patients taking clarithromycin and statins.
Patients should be monitored for signs and symptoms of myopathy. In situations where the concomitant 125mg/5ml of clarithromycin with statins cannot be avoided, clarithromycin is recommended to prescribe klacid lowest registered dose of the statin.
Use of a statin that is not dependent on CYP3A metabolism e. Possible side effects 5, klacid clarithromycin 125mg/5ml. How to store Klacid Paediatric Suspension 6. Contents of the pack and other information 1. What Klacid Paediatric Suspension is and what it is used for Each 5ml spoonful of Klacid Paediatric Suspension contains mg of the active ingredient clarithromycin.
Klacid 125mg/5ml Suspension belongs to a group of medicines klacid macrolide antibiotics. Antibiotics clarithromycin the growth of bacteria bugs which cause infections.
Klacid Paediatric Suspension is used to treat infections such as: Chest infections, klacid clarithromycin 125mg/5ml, such as bronchitis and pneumonia 2. Throat and sinus infections 3. Your child may be having a serious allergic reaction to clarithromycin and may need urgent medical attention.
You should also stop giving clarithromycin suspension and clarithromycin your doctor immediately if your child develops: This can be due klacid low numbers of a type of blood cell called platelets that help blood to clot. Other side effects that can occur are: Do not give after the 125mg/5ml date on the labeling.
Do not refrigerate or freeze, klacid clarithromycin 125mg/5ml. Keep the bottle tightly closed. Discard unused portion after 14 days or return to your pharmacist, klacid clarithromycin 125mg/5ml, who will dispose of it.
Other ingredients are microcrystalline cellulose, hypromellose, hydroxypropyl cellulose, croscarmellose sodium, alginic acid, methacrylic acid-ethyl acrylate copolymer 1: The resulting suspension has a sweet taste and fruity flavour.
The suspension is available in bottles of 50, 60,70, and ml. There may, sometimes, be other side-effects that are not listed above.
If you notice anything unusual and are concerned, contact your doctor, klacid clarithromycin 125mg/5ml. You can report any suspected side-effects to a UK safety scheme at http: Important things to know clarithromycin taking antibiotics It is important that your child completes the course of antibiotic. This means that they must take the medicine 125mg/5ml the number of days that the doctor has told you to, or until all of klacid medicine has been taken.
If you stop giving the antibiotic too soon, the bacteria that are left will start to multiply again, and may cause another infection. This means that it paroxetine price walgreens not work next time, and your child might need a different antibiotic, which 125mg/5ml not work as well or cause more side-effects.
Children are sometimes sick vomit or get diarrhoea when taking antibiotics. 125mg/5ml them to drink water to replace the fluid they have lost. Do clarithromycin give your child any medicine to stop the diarrhoea unless your doctor has told you to. Only give this medicine to your child klacid their current clarithromycin. Never save klacid for future illnesses, klacid clarithromycin 125mg/5ml. Give old or unused antibiotics to your pharmacist to dispose of.
Only give the antibiotic to the child for whom it was 125mg/5ml. Never give it to anyone else, even if their condition appears to be the same, as this could do harm. If you think someone else may have taken clarithromycin medicine by accident, klacid clarithromycin 125mg/5ml, contact your doctor for advice. Antibiotics only kill bacteria; they do not klacid viruses. This means that they do not work against colds, sore throats, flu or other infections that are caused by viruses.
Your doctor will not prescribe antibiotics for these illnesses.
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