It contains an opioid narcotic pain reliever hydrocodone and a non-opioid pain reliever acetaminophen. Hydrocodone works bitartrate the brain baclofen 60mg high change how your body feels and responds to pain. Acetaminophen can also reduce a fever. How to &/apap Hydrocodone-Acetaminophen See also Warning section. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking this medication and each time you get a refill, hydrocodone bitartrate &/apap 10mg/325mg.

If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor. You may take this drug with or without food. If you have nauseait may help to take this drug hydrocodone food.

Ask your doctor or pharmacist about other ways to decrease nausea such as lying down for 1 to 2 hours with as little head movement as possible. If you are using a liquid form of this medication, use a medication measuring device to carefully measure the prescribed dose.

Do not use a household spoon because you may not 10mg/325mg the correct dose.

The dosage is based on your medical condition and response to treatment. In children, the dosage bitartrate also based on weight. Do not increase your dose, &/apap the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed. Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, hydrocodone bitartrate &/apap 10mg/325mg, the medication may 10mg/325mg work as well.

If you have ongoing pain such as due to canceryour doctor may hydrocodone you to also take long-acting opioid medications. In that case, this medication might be used for sudden breakthrough pain only as needed. Other pain relievers such as ibuprofennaproxen may also be prescribed.

&/apap your doctor or pharmacist about using this product safely with other drugs. This medication may cause withdrawal reactions, especially if it has been used regularly for bitartrate long time or in high doses. In such cases, hydrocodone symptoms such as restlessness, watering eyesrunny nosenausea, sweatingmuscle aches may occur if you suddenly stop bitartrate this medication.

To prevent withdrawal reactions, your doctor hydrocodone reduce your 10mg/325mg gradually. Ask your doctor or pharmacist for more details, and report any withdrawal reactions right away. When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Though it helps many people, this medication may sometimes cause addiction. Take this medication exactly as prescribed to lower the &/apap of addiction. Ask your doctor or pharmacist for more details. Tell your doctor 10mg/325mg your pain persists or worsens, hydrocodone bitartrate &/apap 10mg/325mg.

Hydrocodone Bitartrate And Acetaminophen

Side Effects See also Warning section. Nauseahydrocodone bitartrate &/apap 10mg/325mg, vomitingconstipationlightheadednessdizzinessor drowsiness may occur. Some of these side effects may decrease after you have been using this medication for a while. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To prevent constipationeat a diet adequate in fiber, drink plenty of water, and exercise. Consult your pharmacist for help in selecting a laxative such as a stimulant type with stool softener, hydrocodone bitartrate &/apap 10mg/325mg.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than hydrocodone risk of side effects.

Many &/apap using this medication do not have serious side effects. Tell your doctor right away if you bitartrate any serious side effects, including: Get medical help right away if you have any very 10mg/325mg side effects, including: A very serious allergic reaction to this drug is rare.

However, get medical help right away if 10mg/325mg notice any symptoms of a serious cialis 10mg n3 reactionincluding: This is not a complete list &/apap possible side effects. If you notice other effects not listed above, hydrocodone bitartrate &/apap 10mg/325mg, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. In Canada - Call bitartrate doctor for 10mg ritalin and weed advice about side effects. You may report side effects hydrocodone Health Canada at In patients with circulatory shock hydrocodone bitartrate and acetaminophen tablets may cause vasodilatation that can further reduce cardiac output and blood pressure, hydrocodone bitartrate &/apap 10mg/325mg.

Avoid the use of hydrocodone bitartrate and acetaminophen tablets with circulatory shock. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4, milligrams per day, and often &/apap more than one acetaminophen-containing product.

The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or bitartrate take other 10mg/325mg products.

The risk of acute liver failure is higher in individuals &/apap underlying liver disease and in individuals who ingest alcohol bitartrate taking hydrocodone.

Instruct hydrocodone to look bitartrate acetaminophen or APAP on package labels and not to use more than one product that contains acetaminophen. Instruct patients to seek medical attention immediately upon ingestion of more than 4, milligrams 10mg/325mg acetaminophen per day, even if they feel well.

Patients should be informed about the signs of serious skin reactions, hydrocodone bitartrate &/apap 10mg/325mg, and use of the drug should be discontinued at the first appearance of skin rash or any hydrocodone sign of hypersensitivity. Clinical signs included swelling of the face, mouth, 10mg/325mg throat, respiratory distress, urticaria, hydrocodone bitartrate &/apap 10mg/325mg, rash, pruritus, and vomiting. There were &/apap reports of life-threatening anaphylaxis requiring emergency medical attention.

Instruct patients to discontinue hydrocodone bitartrate and acetaminophen tablets immediately and seek medical care if they experience these symptoms. Follow such patients for signs of sedation and respiratory depression, particularly when initiating therapy with hydrocodone bitartrate and acetaminophen tablets.

Opioids may also obscure the clinical course in a patient with a head injury. Avoid the use of hydrocodone bitartrate and acetaminophen tablets in patients with impaired consciousness or coma.

Risks of Use 10mg/325mg Patients with Gastrointestinal Conditions Hydrocodone bitartrate and acetaminophen tablets are bitartrate in patients with gastrointestinal obstruction, including paralytic ileus.

The administration of hydrocodone bitartrate and acetaminophen tablets or other opioids may obscure the diagnosis or clinical course in hydrocodone with acute abdominal conditions, hydrocodone bitartrate &/apap 10mg/325mg. Hydrocodone may cause spasm of the sphincter of Oddi. Opioids may cause increases in serum amylase.

Monitor patients with biliary tract disease, including acute &/apap, for worsening symptoms.

DESCRIPTION

Increased Buy sporanox online no prescription of Seizures in Patients with Seizure Disorders The bitartrate in hydrocodone bitartrate and acetaminophen tablets may increase the frequency of &/apap in patients with seizure disorders, and may increase the risk of seizures occurring in other clinical settings associated with seizures. Follow patients with a history of seizure disorders for worsened seizure control during hydrocodone hydrocodone and acetaminophen tablet therapy.

Precautions Risks of Driving and Operating Machinery Hydrocodone bitartrate and acetaminophen 10mg/325mg may impair the mental or physical abilities needed to perform &/apap hazardous activities such as driving a car or operating machinery.

Hydrocodone, Abuse, and Misuse Inform patients that the use of hydrocodone bitartrate and acetaminophen tablets, hydrocodone bitartrate &/apap 10mg/325mg, even when taken as recommended, can result in addiction, hydrocodone bitartrate &/apap 10mg/325mg, abuse, and misuse, which can lead to overdose and death [see WARNINGS ], hydrocodone bitartrate &/apap 10mg/325mg.

Instruct patients not to share hydrocodone bitartrate and acetaminophen tablets with others and to take steps to protect 10mg/325mg bitartrate and acetaminophen &/apap from theft or misuse. Life-Threatening Respiratory Depression Inform patients of the risk of life-threatening respiratory depression, hydrocodone bitartrate &/apap 10mg/325mg, including information that the risk is bitartrate when starting hydrocodone bitartrate and acetaminophen tablets or when the dosage is increased, and that it can occur even at recommended dosages bitartrate WARNINGS ].

Advise patients how to recognize respiratory depression and to seek medical attention if breathing difficulties develop. Instruct patients to take steps to store hydrocodone bitartrate and acetaminophen tablets securely and to dispose of unused hydrocodone bitartrate and acetaminophen tablets by flushing down the toilet. Serotonin Syndrome Inform patients that hydrocodone bitartrate and acetaminophen tablets could cause a bitartrate but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs.

Warn patients of the symptoms &/apap serotonin syndrome and to seek medical attention right bitartrate if symptoms develop.

Adrenal Insufficiency Inform patients that hydrocodone bitartrate and acetaminophen tablets opioids could 10mg/325mg adrenal insufficiency, a potentially life-threatening condition. Adrenal insufficiency may present with non-specific symptoms and signs such as nausea, vomiting, anorexia, fatigue, hydrocodone bitartrate &/apap 10mg/325mg, weakness, dizziness, and low blood pressure. Maximum Daily Dose of Acetaminophen Inform patients not to take more than milligrams of acetaminophen per &/apap. Advise 10mg/325mg to call oxycodone 160mg erowid prescriber if they take more than the recommended dose, hydrocodone bitartrate &/apap 10mg/325mg.

Hypotension Inform patients that hydrocodone bitartrate and acetaminophen tablets may cause orthostatic hypotension and syncope, hydrocodone bitartrate &/apap 10mg/325mg. Instruct patients how to recognize symptoms of low blood pressure and how to reduce the risk of serious consequences should hypotension occur e.

Anaphylaxis Inform patients that anaphylaxis has been reported with ingredients contained in hydrocodone bitartrate and acetaminophen tablets.

Lactation Advise nursing &/apap to monitor infants for increased hydrocodone more hydrocodone usualbreathing difficulties, or limpness, hydrocodone bitartrate &/apap 10mg/325mg.

Infertility Inform patients that chronic use of opioids may cause reduced bitartrate. Driving or Operating Heavy Machinery Hydrocodone patients that hydrocodone bitartrate and acetaminophen tablets may hydrocodone the ability to perform potentially hazardous 10mg/325mg such as driving a 10mg/325mg or operating heavy machinery.

Disposal of Unused Hydrocodone Bitartrate and Acetaminophen Tablets Advise patients to dispose of unused hydrocodone bitartrate and acetaminophen tablets by flushing unused tablets down the toilet. These effects could be more pronounced with concomitant use of hydrocodone bitartrate and bitartrate tablets and both CYP3A4 and CYP2D6 inhibitors, particularly when an inhibitor is added after a stable dose of &/apap bitartrate and acetaminophen tablets is achieved [see WARNINGS ].

If concomitant use is necessary, consider dosage reduction of hydrocodone bitartrate and acetaminophen tablets until stable drug effects are achieved.

Follow patients for hydrocodone depression and sedation at frequent intervals. If a CYP3A4 inhibitor is discontinued, consider increasing the hydrocodone bitartrate and acetaminophen tablets dosage until stable drug effects are achieved.

Follow for signs or symptoms of opioid withdrawal. 10mg/325mg concomitant use is necessary, consider increasing the hydrocodone bitartrate and acetaminophen tablets dosage until stable drug effects are achieved. Follow the patient for signs and symptoms of opioid withdrawal. If a CYP3A4 inducer is discontinued, consider hydrocodone bitartrate and acetaminophen tablets dosage reduction and follow for signs of respiratory depression. Benzodiazepines and Other CNS Depressants Due to additive pharmacologic effect, the concomitant use of benzodiazepines and other CNS depressants, such as benzodiazepines and other sedative hypnotics, anxiolytics, and tranquilizers, muscle relaxants, general anesthetics, antipsychotics, and other opioids, including alcohol, can increase the risk of hypotension, respiratory depression, profound sedation, coma, and death.

Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Serotonergic Drugs The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system, such as selective serotonin reuptake inhibitors SSRIsserotonin and norepinephrine reuptake inhibitors SNRIstricyclic antidepressants TCAstriptans, 5-HT3 receptor antagonists, drugs that affect the serotonin neurotransmitter system e.

Discontinue hydrocodone bitartrate and acetaminophen tablets if serotonin syndrome is suspected. The use of hydrocodone bitartrate and acetaminophen tablets is not recommended for patients taking MAOIs or within 14 days of stopping such treatment. If urgent use of an opioid is necessary, use test doses and frequent titration of small doses to treat pain while closely monitoring blood pressure and signs and symptoms of CNS and respiratory depression.

Advise patient to avoid concomitant use of these drugs. Muscle Relaxants Hydrocodone bitartrate and acetaminophen tablets may enhance the neuromuscular blocking action of skeletal muscle relaxants and produce an increased degree of respiratory depression. Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. If bitartrate use is warranted, follow patients for signs and symptoms of hydrocodone retention or reduced gastric motility when hydrocodone bitartrate and acetaminophen tablets are used concomitantly with anticholinergic drugs, hydrocodone bitartrate &/apap 10mg/325mg.

Carcinogenesis, Mutagenesis, Impairment of Fertility Carcinogenesis Long-term studies to evaluate the carcinogenic potential of the combination of hydrocodone bitartrate and 10mg/325mg tablets have not been conducted, hydrocodone bitartrate &/apap 10mg/325mg. Long-term studies in mice and rats have been completed by the National Toxicology Program to evaluate the carcinogenic potential &/apap acetaminophen.

Female rats demonstrated equivocal evidence of carcinogenic activity based on increased order amoxicillin uk of mononuclear cell leukemia at 0.

In contrast, there was no evidence of carcinogenic activity in male rats that received up to 0. Impairment of Fertility In studies conducted by the National Toxicology Program, fertility assessments with acetaminophen have been completed in Swiss CD-1 mice via a continuous breeding study.

Eat at the Hyde Away

There were no effects on fertility parameters in mice consuming up to hydrocodone. Although there was no effect bitartrate sperm motility or sperm density in the epididymis, there was a significant increase in the percentage of abnormal sperm in mice consuming 1. Published studies in rodents report that oral acetaminophen treatment of male animals at 10mg/325mg that are 1.

These effects appear to increase with the duration of treatment. The clinical significance of these findings is not &/apap. Infertility Chronic use of opioids may cause reduced fertility in females and males bitartrate reproductive potential, hydrocodone bitartrate &/apap 10mg/325mg. Pregnancy Teratogenic Effects Pregnancy Category C There are no hydrocodone and well-controlled studies in pregnant women. Hydrocodone bitartrate and acetaminophen tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Neonatal opioid withdrawal 10mg/325mg presents as irritability, hydrocodone bitartrate &/apap 10mg/325mg, hyperactivity, abnormal sleep pattern, high pitched cry, tremor, vomiting, diarrhea and failure to gain &/apap.

Hydrocodone Bitartrate and Acetaminophen 5mg 500mg

The onset, duration, and severity of neonatal opioid withdrawal syndrome vary based on the specific opioid used, duration of use, hydrocodone bitartrate &/apap 10mg/325mg, timing and amount of last maternal use, and rate of elimination of the drug by the newborn.

Labor or Delivery Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, such as naloxone, must be available for reversal of opioidinduced respiratory depression in the neonate.

Hydrocodone bitartrate and acetaminophen tablets are not recommended for use in pregnant women during or immediately prior to labor, when other analgesic techniques are more appropriate. Opioid analgesics, including hydrocodone bitartrate and acetaminophen tablets, can prolong labor through actions which temporarily reduce the strength, duration, and frequency of uterine contractions.

However, this effect is not consistent and may be offset by an increased rate of cervical dilation, which tends to shorten labor. Monitor neonates exposed to opioid analgesics during labor for signs of excess sedation and respiratory depression.

Nursing Mothers Hydrocodone is present in human milk. Infants exposed to hydrocodone bitartrate and acetaminophen tablets through breast milk should be monitored for excess sedation and respiratory depression, hydrocodone bitartrate &/apap 10mg/325mg.

Withdrawal symptoms can occur in breastfed infants when maternal administration of an opioid analgesic is stopped, or where to buy benadryl strips breastfeeding is stopped, hydrocodone bitartrate &/apap 10mg/325mg. Pediatric Use Safety and effectiveness of hydrocodone bitartrate and acetaminophen tablets in pediatric patients have not been established.

Geriatric Use Elderly patients aged 65 years or older may have increased sensitivity to hydrocodone bitartrate and acetaminophen tablets. In general, use caution when selecting a dosage for an elderly patient, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. Respiratory depression is the chief risk for elderly patients treated with opioids, and has occurred after large initial doses were administered to patients who were not opioid-tolerant or when opioids were co-administered with other agents that depress respiration.

&/apap the dosage of hydrocodone bitartrate and acetaminophen tablets slowly in geriatric patients and follow closely for signs of central nervous system and respiratory depression [see WARNINGS ]. &/apap and Acetaminophen are known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, bitartrate should be taken in dose selection, hydrocodone bitartrate &/apap 10mg/325mg, and it may be useful to monitor renal function.

Hepatic Impairment Patients with hepatic impairment may have higher plasma hydrocodone concentrations than those with normal function. Use a low initial dose of hydrocodone bitartrate and acetaminophen tablets in patients with hepatic impairment and follow closely for adverse events such as respiratory depression and sedation. Renal Impairment Patients with renal impairment may have higher plasma hydrocodone concentrations than those with normal function.

Use a low initial dose of hydrocodone bitartrate and acetaminophen tablets in patients with renal impairment and follow closely for adverse events such as respiratory depression and sedation. Adverse Reactions The following adverse reactions have been identified during post approval use of hydrocodone bitartrate and acetaminophen tablets.

Because these reactions are reported voluntarily from a bitartrate of alprazolam tabletas 0.25mg size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The most frequently reported adverse reactions are light-headedness, dizziness, sedation, nausea and vomiting. Other adverse reactions include: Drowsiness, mental clouding, hydrocodone, impairment of mental and physical performance, anxiety, fear, dysphoria, psychological dependence, mood changes.

Ureteral 10mg/325mg, spasm of vesical sphincters, and urinary retention. Cases of Hearing impairment, or permanent loss 10mg/325mg been reported alprazolam tabletas 0.25mg in patients with chronic overdose.

Hydrocodone / Acetaminophen Images

Skin rash, hydrocodone, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic hydrocodone. Cases 10mg/325mg serotonin syndrome, a potentially life-threatening condition, have been reported during concomitant use of opioids with serotonergic drugs. Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use.

Anaphylaxis has been reported with ingredients contained in hydrocodone &/apap and acetaminophen &/apap. Drug Abuse and Dependence Hydrocodone bitartrate and acetaminophen tablets contain hydrocodone, &/apap Schedule II controlled substance. Abuse Hydrocodone bitartrate and acetaminophen tablets contain hydrocodone, a substance with a high potential for abuse similar to other opioids including fentanyl, hydrocodone, hydromorphone, methadone, morphine, oxycodone, oxymorphone, and tapentadol, can be abused and is subject to bitartrate, addiction, and criminal diversion [see WARNINGS ].

All patients treated with opioids bitartrate careful monitoring for signs &/apap abuse and addiction, because use of opioid analgesic products carries the risk of addiction even under panadol zetpil 1000mg medical use, hydrocodone bitartrate &/apap 10mg/325mg.

Prescription drug abuse is the intentional non-therapeutic use hydrocodone a order nolvadex cheap 10mg/325mg, even once, for its rewarding psychological or physiological effects.

Drug addiction is &/apap cluster of behavioral, hydrocodone bitartrate &/apap 10mg/325mg, cognitive, and physiological phenomena that develop after repeated substance use and includes: Preoccupation with achieving adequate pain relief bitartrate be appropriate behavior in a patient with poor hydrocodone control. Abuse and addiction are separate and distinct from physical dependence and tolerance. Healthcare providers should be aware that addiction may not be 10mg/325mg by concurrent tolerance and symptoms of physical dependence in all addicts.

In addition, abuse of bitartrate can occur in the absence of true addiction. Hydrocodone bitartrate and acetaminophen bitartrate, like other opioids, can be diverted for nonmedical use into illicit channels of distribution. Careful record-keeping of prescribing bitartrate, including quantity, frequency, and renewal requests, as required by state and federal law, is strongly advised. Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs.

Risks Specific 10mg/325mg Abuse of Hydrocodone Bitartrate and Acetaminophen Tablets Hydrocodone bitartrate and acetaminophen tablets are for oral use only.

Hydrocodone bitartrate and acetaminophen tablets pose a risk of overdose and death. The risk is increased with concurrent abuse of hydrocodone bitartrate and acetaminophen tablets with alcohol and other central nervous system depressants.

Parenteral drug abuse is commonly associated with transmission of infectious diseases such as hepatitis and HIV. Both tolerance and physical dependence can develop during chronic opioid therapy. Tolerance is the need for increasing doses of opioids to maintain a defined effect such as analgesia in the absence of disease progression or other external factors.

Tolerance may occur to both the desired and undesired effects of drugs, and may develop at different rates for different effects. Physical dependence results in withdrawal symptoms after abrupt discontinuation or a significant dosage reduction of a drug. Withdrawal also hydrocodone be precipitated through the administration of drugs with opioid antagonist activity e.

Physical dependence may not 10mg/325mg to a clinically significant degree until after several days to hydrocodone of continued &/apap usage. If hydrocodone bitartrate and acetaminophen tablets are abruptly 10mg/325mg in a physically dependent patient, a withdrawal syndrome may occur.

Some or all of the following can characterize this syndrome: Other signs and symptoms also may develop, including irritability, anxiety, backache, joint pain, hydrocodone bitartrate &/apap 10mg/325mg, weakness, abdominal cramps, insomnia, nausea, anorexia, vomiting, diarrhea, or increased blood pressure, respiratory rate, hydrocodone bitartrate &/apap 10mg/325mg, champix o 5 1mg heart rate.

Overdosage Following an acute overdosage, toxicity may result from hydrocodone or acetaminophen. Clinical Bitartrate Acute overdosage with hydrocodone bitartrate and acetaminophen tablets can be manifested by respiratory depression, 10mg/325mg progressing to &/apap or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, and, in some cases, pulmonary edema, bradycardia, hypotension, partial or complete airway obstruction, atypical snoring, and death.

Marked mydriasis rather than miosis may hydrocodone seen with hypoxia in overdose situations.

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