Your doctor will want to discuss your treatment from time to time. Arcoxia can increase blood pressure in some people, especially in high doses, and this could increase the risk of heart attacks and strokes. Your doctor will want to check your blood pressure from time to time, to make sure that it is safe to continue treatment. Your doctor may have prescribed Arcoxia for another reason. Ask your doctor if you have any questions about why Arcoxia has been prescribed for you.
Arcoxia is not addictive. Do not take Arcoxia if: If you take this medicine after the expiry date has passed, it may not work. You have had heart failure, a heart attack, bypass surgery, chest pain angina , narrow or blocked arteries of the extremities peripheral arterial disease , a stroke or mini stroke TIA or transient ischaemic attack.
You have high blood pressure that is not well controlled on blood pressure medication. You are having major surgery and have conditions which increase your risk of coronary artery disease or atherosclerosis such as high blood pressure, diabetes, high cholesterol or smoking. You are having major surgery on you heart or arteries. If you are not sure whether you should start taking Arcoxia, talk to your doctor. Arcoxia has not been adequately studied in children. Therefore, Arcoxia should not be given to children.
Arcoxia works equally well in older and younger adult patients. Adverse experiences may occur at a higher incidence in older patients compared to younger patients. If you are elderly ie over 65 years of age , your doctor will want to appropriately keep a check on you. No dosage adjustment is necessary for older patients. Before you start to taking Arcoxia tell your doctor if: Arcoxia is not recommended for use during late pregnancy.
If there is a need to consider using Arcoxia during your pregnancy, your doctor will discuss with you the benefits and risks of using it.
It is not known if Arcoxia passes into breast milk. You and your doctor should discuss whether you should stop breast-feeding or not take Arcoxia. If you have not told your doctor about any of the above, tell them before you take any Arcoxia.
Tell your doctor if you are taking any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines and Arcoxia may interfere with each other. You may need different amounts of your medicine, or you may need to take different medicines.
There is a further increase in the risk of gastrointestinal adverse effects gastrointestinal ulceration or other gastrointestinal complications when etoricoxib is taken concomitantly with acetylsalicylic acid even at low doses. Cardiovascular effects Clinical trials suggest that the selective COX-2 inhibitor class of drugs may be associated with a risk of thrombotic events especially myocardial infarction MI and stroke , relative to placebo and some NSAIDs. As the cardiovascular risks of etoricoxib may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used.
Patients with significant risk factors for cardiovascular events e. COX-2 selective inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effect. Therefore antiplatelet therapies should not be discontinued see sections above, 4.
Renal effects Renal prostaglandins may play a compensatory role in the maintenance of renal perfusion. Therefore, under conditions of compromised renal perfusion, administration of etoricoxib may cause a reduction in prostaglandin formation and, secondarily, in renal blood flow, and thereby impair renal function.
Patients at greatest risk of this response are those with pre-existing significantly impaired renal function, uncompensated heart failure, or cirrhosis. Monitoring of renal function in such patients should be considered. Fluid retention, oedema and hypertension As with other medicinal products known to inhibit prostaglandin synthesis, fluid retention, oedema and hypertension have been observed in patients taking etoricoxib.
For information regarding a dose related response for etoricoxib see section 5. Caution should be exercised in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension and in patients with pre-existing oedema from any other reason. If there is clinical evidence of deterioration in the condition of these patients, appropriate measures including discontinuation of etoricoxib should be taken. Etoricoxib may be associated with more frequent and severe hypertension than some other NSAIDs and selective COX-2 inhibitors, particularly at high doses.
Therefore, hypertension should be controlled before treatment with etoricoxib see section 4. Blood pressure should be monitored within two weeks after initiation of treatment and periodically thereafter. If blood pressure rises significantly, alternative treatment should be considered.
If signs of hepatic insufficiency occur, or if persistently abnormal liver function tests three times the upper limit of normal are detected, etoricoxib should be discontinued. General If during treatment, patients deteriorate in any of the organ system functions described above, appropriate measures should be taken and discontinuation of etoricoxib therapy should be considered.
Medically appropriate supervision should be maintained when using etoricoxib in the elderly and in patients with renal, hepatic, or cardiac dysfunction.
Caution should be used when initiating treatment with etoricoxib in patients with dehydration. It is advisable to rehydrate patients prior to starting therapy with etoricoxib. Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported very rarely in association with the use of NSAIDs and some selective COX-2 inhibitors during post-marketing surveillance see section 4.
Patients appear to be at highest risk for these reactions early in the course of therapy with the onset of the reaction occurring in the majority of cases within the first month of treatment. Serious hypersensitivity reactions such as anaphylaxis and angioedema have been reported in patients receiving etoricoxib see section 4. Some selective COX-2 inhibitors have been associated with an increased risk of skin reactions in patients with a history of any drug allergy.
Etoricoxib should be discontinued at the first appearance of skin rash, mucosal lesions, or any other sign of hypersensitivity. There are different strengths available for this medicinal product and depending on your disease your doctor will prescribe the tablet strength that is appropriate for you.
The recommended dose is: The recommended dose is 30mg once a day, increase to a maximum of 60mg once a day if needed.
The recommended dose is 90mg once a day. Acute pain conditions Etoricoxib should be used only for the acute painful period. The recommended dose is mg once a day which should only be used for the acute painful period, limited to a maximum of 8 days treatment.
Postoperative dental surgery pain The recommended dose is 90mg once daily, limited to a maximum of 3 days treatment. If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.
If you have a heart condition or a problem with your blood vessels or circulation. If you have high blood pressure. If you have high blood sugar or cholesterol levels. If you have any blood clotting problems. If you have a connective tissue disorder such as systemic lupus erythematosus. This is an inflammatory condition which is also called lupus or SLE. If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as as herbal and complementary medicines.
If you have ever had an allergic reaction to any other NSAID such as aspirin, ibuprofen, diclofenac, and indometacin , or to any other medicine. How to take etoricoxib Before you start taking etoricoxib, read the manufacturer's printed information leaflet from inside the pack.
It will give you more information about the tablets, and it will also provide you with a full list of the side-effects which you could experience from taking them. Take etoricoxib once each day, exactly as your doctor tells you to. There are four strengths of tablet available - 30 mg, 60 mg, 90 mg and mg.
You will be prescribed the strength of tablet that suits your condition. People with osteoarthritis are usually prescribed 30 mg once-daily, although the dose can be increased to 60 mg if needed.
People with rheumatoid arthritis or ankylosing spondylitis are prescribed 60 mg once-daily, although the dose can be increased to 90 mg if it becomes necessary. If you are taking etoricoxib for gout, you will be prescribed a short course of mg strength tablets to take once-daily for up to eight days.
Although this interaction has not been studied tablet etoricoxib, coadministration of cyclosporin or tacrolimus with any NSAID may increase the nephrotoxic effect of cyclosporin or tacrolimus. If arcoxia buy any medicines, check with a pharmacist that they are suitable for you to take. General If during treatment, arcoxia 30mg tablets, patients deteriorate in any of the organ system functions described above, appropriate measures should be taken and discontinuation of etoricoxib therapy should be considered. NSAIDs may reduce the effect of diuretics and other antihypertensive drugs. In clinical trials for acute gouty arthritis, etoricoxib was given for 8 days. Arcoxia is not addictive. Clinical experience is limited particularly in patients with moderate hepatic dysfunction and caution is advised. Etoricoxib is 30mg in the milk of lactating rats. Arcoxia comes as tablets. If you have any blood clotting problems. It is important that you use the lowest dose that controls your pain and you should not take Arcoxia for longer than necessary. Tell your doctor if you are taking any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop. Weight - your doctor may suggest losing some weight to help reduce the strain on your joints.
The recommended dose is mg tablet a day which should only be used for the acute 30mg period, limited to a maximum of 8 days treatment. If you experience 30mg other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist for further advice. Your doctor will want to discuss your treatment from time to time. 30mg of etoricoxib mg with hormone replacement therapy consisting of conjugated tablets 0. The decision to prescribe a selective COX-2 tablet should arcoxia based on an assessment of the individual patient's overall risks see sections 4, arcoxia 30mg tablets. It is important that you use the lowest dose that controls your pain and you should not take Arcoxia for longer than necessary. If you become pregnant while taking Arcoxia, tell your doctor immediately. In arcoxia precio cytotec misoprostol argentina for acute postoperative dental pain following surgery including patients treated with etoricoxib 90 mg or mgarcoxia 30mg tablets, the adverse experience profile in these studies was generally tablet to that reported in the combined OA, RA, and chronic arcoxia back pain studies. It is advisable to rehydrate patients prior to starting therapy with etoricoxib. This should be considered when rapid symptomatic relief is needed, arcoxia 30mg tablets. Therefore, the daily doses stated above for each condition should not be exceeded. Breast —feeding It is not known if Arcoxia is excreted in human milk, arcoxia 30mg tablets. Etoricoxib is excreted in the milk of lactating rats. Acute pain conditions Etoricoxib should be arcoxia only for the acute painful period. In patients with moderate hepatic dysfunction Child-Pugh scoreregardless of indication, arcoxia 30mg tablets, the dose of 30 mg once daily should not be exceeded. The potential for human risk in pregnancy is 30mg.
Do not drive if you experience dizziness or sleepiness. Doses greater than those 30mg for each condition have either not demonstrated additional efficacy or have not been studied. Depending on your condition, you may need to take Arcoxia for a few days or for a longer tablet. 30mg your doctor if you have any questions about why Arcoxia has been prescribed for you. Before taking etoricoxib Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is arcoxia. Some people developed ulcers whether they were taking Arcoxia or placebo in these studies; however the rate was higher on Arcoxia. Breast —feeding It is not known if Arcoxia is excreted in tablet milk. Antacids do not affect the pharmacokinetics of etoricoxib to a clinically relevant extent. Take the container with you, arcoxia 30mg tablets, even arcoxia it is empty.
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