Patients, especially individuals with a history of seizures or epilepsy , should not be abruptly discontinued from any CNS depressant agent, including XANAX. Some patients have experienced considerable difficulty in tapering and discontinuing from XANAX, especially those receiving higher doses for extended periods. As with all anxiolytics, repeat prescriptions should be limited to those who are under medical supervision.

These include a spectrum of withdrawal symptoms ; the most important is seizure see Drug Abuse And Dependence. Even after relatively shortterm use at the doses recommended for the treatment of transient anxiety and anxiety disorder ie, 0. However, in a controlled postmarketing discontinuation study of panic disorder patients, the duration of treatment 3 months compared to 6 months had no effect on the ability of patients to taper to zero dose.

The importance of dose and the risks of XANAX as a treatment for panic disorder Because the management of panic disorder often requires the use of average daily doses of XANAX above 4 mg, the risk of dependence among panic disorder patients may be higher than that among those treated for less severe anxiety. Experience in randomized placebo-controlled discontinuation studies of patients with panic disorder showed a high rate of rebound and withdrawal symptoms in patients treated with XANAX compared to placebo-treated patients.

Relapse or return of illness was defined as a return of symptoms characteristic of panic disorder primarily panic attacks to levels approximately equal to those seen at baseline before active treatment was initiated.

Rebound refers to a return of symptoms of panic disorder to a level substantially greater in frequency, or more severe in intensity than seen at baseline. Withdrawal symptoms were identified as those which were generally not characteristic of panic disorder and which occurred for the first time more frequently during discontinuation than at baseline. In a controlled clinical trial in which 63 patients were randomized to XANAX and where withdrawal symptoms were specifically sought, the following were identified as symptoms of withdrawal: Other symptoms, such as anxiety and insomnia, were frequently seen during discontinuation, but it could not be determined if they were due to return of illness, rebound, or withdrawal.

Alprazolam is not approved for use by anyone younger than 18 years old. How should I take alprazolam? Take alprazolam exactly as prescribed by your doctor. Follow all directions on your prescription label.

Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. Do not swallow the orally disintegrating tablet whole.

Allow it to dissolve in your mouth without chewing. The physical dependence and withdrawal syndrome of alprazolam also add to its addictive nature. In the small subgroup of individuals who escalate their doses there is usually a history of alcohol or other substance use disorders. Men and women are equally likely to use benzodiazepines recreationally. The report found that alprazolam is the most common benzodiazepine for recreational use, followed by clonazepam , lorazepam , and diazepam.

These uses include aids to relieve the panic or distress of dysphoric " bad trip " reactions to psychedelic drugs , such as LSD , and the drug-induced agitation and insomnia in the " comedown " stages of stimulant use, such as amphetamine , cocaine , and MDMA allowing sleep. What are the effects of taking Xanax and over-the-counter drugs, such as vitamin C, Caltrate, zinc, and Metamucil?

There are no known drug interactions found between Xanax alprazolam and the following over-the-counter medications: Talk to your doctor if you have any concerns about your prescription or over-the-counter medications. Do not start or stop any medications or treatments without first talking to your doctor. I believe you will find the following links at everydayhealth. Is long term use 20 years of Xanax harmful?

I wouldn't say that it is harmful. Obviously it depends on the dose and frequency the medication is taken. In many cases, taking a Xanax alprazolam would be preferable than having alcoholic beverage for some people. I always recommend having yearly check ups with your physician and having both kidney and liver function tests performed.

However, I have yet to run into any serious consequences for people using Xanax for 20 years. Abusing the medication is a different story. Feel free to visit us here for more information: What are the possibilities of having a seizure if you take Xanax? According to Clinical Pharmacology, when taken at the recommended dose, an uncommon side effect of Xanax Alprazolam is seizures.

This side effect was reported in less than 1 percent of patients taking alprazolam in clinical studies. With short-term and long-term use of alprazolam, patients may experience withdrawal symptoms including seizures. If you experience a seizure while taking alprazolam, it is considered a serious side effect and you should contact your doctor immediately.

To minimize the possibilities of this serious side effect, alprazolam should be taken only as prescribed and not with any other drugs that affect brain chemicals unless they are prescribed by a doctor who is aware of all the medications a patient is taking.

It is also important to not take the medication with alcohol. I take 6 mg of Xanax a day, along with calcium, Estroven with a multivitamin in it and flaxseed oil. Am I doing okay with what I am taking? Xanax alprazolam is a highly potent, short-acting benzodiazepine primarily used to treat moderate to severe anxiety disorders e. Generally speaking, drug interactions fall into three main categories: Drug-disease interactions may occur when an existing medical condition makes certain drugs potentially harmful.

Antacids calcium may decrease the serum concentration of benzodiazepines, however, no action is required. For more detailed information, consult with your physician or pharmacist for guidance based on your specific condition and current medications, particularly before taking any action. How long does it take to get Xanax out of your system? The average half life of Xanax alprazolam for adults is approximately The immediate release formulation has a half life range of 6. Half life is defined as the amount of time it requires for approximately one half of the medication to be out of the system.

Most sources state that it takes half lives for a medication to be completely removed from the body after stopping the medication. Therefore it would take approximately 56 hours for the medication to be out of the system. This is just an estimate as there are wide ranges in the half life values for Xanax and elimination of a medication is based on many patient specific variables.

Talk with your health care provider regarding questions and concerns you have about prescription medications. Jen Marsico, RPh Q: What's the difference between tramadol and Xanax?

Tramadol is in a drug class called opiate agonists. Tramadol is used for the management of moderate to moderately severe pain. Tramadol works by altering pain sensation in the body. Xanax alprazolam is in a drug class called benzodiazepines. Xanax is used in the treatment of anxiety disorders and panic disorders. Xanax is thought to work by affecting brain chemicals and lessening abnormal brain excitement. Derek Dore, PharmD Q: Can I take Xanax while pregnant?

Xanax is a pregnancy category D. Xanax can cause birth defects in an unborn baby. Xanax should not be taken during pregnancy without the doctor Q: I have been taking Xanax for 5 years. What are the withdrawal symptoms and how long do they last? Xanax is indicated for anxiety. Common side effects of Xanax include drowsiness, dizziness, dry mouth, muscle weakness, and blurred speech.

Xanax may be habit-forming and should only be taken as the doctor prescribed. Symptoms of anxiety and restlessness may return once the Xanax is discontinued.

Withdrawal symptoms may occur after using Xanax for a long period of time. Withdrawal symptoms include blurred vision, loss of appetite, diarrhea, trouble concentrating, and numbness and tingling. This is not a complete list of the side effects associated with Xanax. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat.

Always keep a current list of the drugs and supplements you take and review it with your healthcare providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products.

This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Tell your health-care provider about any negative side effects from prescription drugs. You can also report them to the U. Food and Drug Administration by visiting www. This means you may be more likely to be drowsy. Your doctor should monitor you closely. Also, you should take extra care to avoid falls that may be caused by drowsiness or dizziness.

This medication has not been studied in children. It should not be used in people younger than 18 years. This dosage information is for alprazolam oral tablet.

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on: Because of its similarity to other benzodiazepines, it is assumed that alprazolam undergoes transplacental passage and that it is excreted in human milk.

Pediatrics — The pharmacokinetics of alprazolam in pediatric patients have not been studied. Gender — Gender has no effect on the pharmacokinetics of alprazolam. Most of the interactions that have been documented with alprazolam are with drugs that inhibit or induce CYP3A4.

Compounds that are potent inhibitors of CYP3A would be expected to increase plasma alprazolam concentrations. Drug products that have been studied in vivo, along with their effect on increasing alprazolam AUC, are as follows: CYP3A inducers would be expected to decrease alprazolam concentrations and this has been observed in vivo.

The oral clearance of alprazolam given in a 0. The ability of alprazolam to induce human hepatic enzyme systems has not yet been determined. However, this is not a property of benzodiazepines in general. Further, alprazolam did not affect the prothrombin or plasma warfarin levels in male volunteers administered sodium warfarin orally.

Alprazolam tablets were significantly better than placebo at each of the evaluation periods of these 4-week studies as judged by the following psychometric instruments: Panic Disorder Support for the effectiveness of alprazolam tablets in the treatment of panic disorder came from three short-term, placebo-controlled studies up to 10 weeks in patients with diagnoses closely corresponding to DSM-III-R criteria for panic disorder.

In two of the three studies, alprazolam tablets were superior to placebo on a variable defined as "change from baseline on the number of panic attacks per week" range, 3. A subgroup of patients who were improved on alprazolam tablets during short-term treatment in one of these trials was continued on an open basis up to 8 months, without apparent loss of benefit.

Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. At least 6 of the following 18 symptoms are often present in these patients:

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