It is also effective in systemic or traumatic herpes infections, eczema herpeticum and Herpes simplex meningitis. Reviews of research dating from the s show there is some effect in reducing the number and duration of lesions if aciclovir is applied at an early stage of an outbreak. This finding emphasizes the importance of testing simple, inexpensive non-ART strategies, such as aciclovir and cotrimoxazole , in people with HIV.
It has been shown in limited test studies that the nursing infant is exposed to approximately 0. Aciclovir mg tablets are used to: Warnings and precautions Talk to your doctor or pharmacist before taking Aciclovir tablets: Other medicines and Aciclovir tablets Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines: Care should be taken if you are taking high doses of Aciclovir, as blood levels of both drugs may increase.
Your doctor may monitor your kidney function. Common aciclovir side-effects these affect less than 1 in 10 people What can I do if I experience this? Feeling sick or being sick vomiting , stomach ache Stick to simple foods - avoid fatty or spicy meals Itchy rash, feeling hot If either are troublesome, speak with your doctor Headache Drink plenty of water and ask your pharmacist to recommend a suitable painkiller.
If the headache continues, speak with your doctor Diarrhoea Drink plenty of water to replace any lost fluids Feeling dizzy or tired Do not drive and do not use tools or machines while affected If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist for further advice.
How to store aciclovir Keep all medicines out of the reach and sight of children. Store in a cool, dry place, away from direct heat and light. Important information about all medicines Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty. This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines. Do not keep out-of-date or unwanted medicines. In severely immunocompromised patients eg after marrow transplant or in patients with impaired absorption from the gut the dose can be doubled to mg aciclovir or alternatively intravenous dosing could be considered. Dosing should begin as early as possible after the start of an infection; for recurrent episodes this should preferably be during the prodromal period or when lesions first appear.
Suppression of herpes simplex infections in immunocompetent patients: Many patients may be conveniently managed on a regime of mg aciclovir twice daily at approximately twelve-hourly intervals.
Dosage titration down to mg aciclovir taken three times daily at approximately eight-hourly intervals or even twice daily at approximately twelve-hourly intervals, may prove effective. Some patients may experience break-through infections on total daily doses of mg aciclovir. Therapy should be interrupted periodically at intervals of six to twelve months, in order to observe possible changes in the natural history of the disease.
Prophylaxis of herpes simplex infections in immunocompromised patients: In severely immunocompromised patients eg after marrow transplant or in patients with impaired absorption from the gut, the dose can be doubled to mg aciclovir or, alternatively, intravenous dosing could be considered.
The duration of prophylactic administration is determined by the duration of the period at risk. Dosage in the paediatric population: Treatment of herpes simplex infections, and prophylaxis of herpes simplex infections in the immunocompromised: Treatment of varicella infection: Children aged years should be given mg four times daily. Children aged 6 years and over should be given mg four times daily.
Treatment should continue for 5 days. A liquid formulation might be more suitable for small children. No specific data are available on the suppression of herpes simplex infections or the treatment of herpes zoster infections in immunocompetent children.
When treatment of herpes zoster infections is required in immunocompromised children, intravenous dosing should be considered. Dosage in the elderly: The possibility of renal impairment in the elderly must be considered and the dosage should be adjusted accordingly see Dosage in renal impairment below.
In the elderly, total aciclovir body clearance declines along with creatinine clearance. Dosage may be reduced in the elderly, especially in those whose kidneys are not working properly. To avoid dehydration, it is important to drink plenty of water whilst taking Aciclovir tablets, especially if you are elderly or taking doses of 4g a day or higher.
If you take more Aciclovir tablets than you should If you take too many Aciclovir tablets, contact your doctor immediately. Signs of an overdose include effects on the stomach and intestines such as feeling or being sick and effects on the nervous system such as confusion.
If you forget to take Aciclovir tablets Do not take a double dose to make up for a forgotten dose. If you forget to take a dose, take it as soon as you remember it and then take the next dose at the right time. Contact your doctor at once if you have a severe allergic reaction anaphylaxis such as swelling of the face, lips, tongue or throat angioedema , difficulty breathing or swallowing.
Aciclovir is active against most species in the herpesvirus family. Herpes simplex viruses viagra buying usa cold sores and genital herpes. 400mg descending order of activity: The clinical relevance of 400mg findings is aciclovir. The first step in this process is dependant on the presence of the HSV-coded thymidine kinase. As aciclovir persists in aciclovir plasma of patients with renal insufficiency, in chronic renal failure this value is increased and may be up to This information has 400mg compiled for use by healthcare practitioners and consumers in the United States. By reporting side effects you can help provide more information on the safety of this medicine. If you forget to take a dose, take it aciclovir soon as you remember and then continue as before. Angioedema, erythema multiforme, Stevens Johnson syndrome, aciclovir bp 400mg, toxic epidermal necrolysis, aciclovir bp 400mg. Ask 400mg pharmacist how to throw away medicines you no longer use, aciclovir bp 400mg. The possibility of renal impairment in the elderly must be considered and the dosage should be adjusted accordingly see Dosage in renal impairment below, aciclovir bp 400mg. If you still feel unwell after finishing the course, go back to see your doctor.
It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since 400mg medicine was packaged. Infrequent adverse effects include erythema or itch. Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Speak with 400mg doctor or pharmacist if any of the following continue or become troublesome. Adequate hydration of elderly patients taking high oral doses of aciclovir should be maintained, aciclovir bp 400mg. Take them to aciclovir local pharmacy which will dispose of them for aciclovir. Pack size is Getting the most from your treatment You should drink plenty while you are on aciclovir to keep your kidneys working well. Although some herpes infections for example, aciclovir bp 400mg, cold sores can be treated with creams or ointments, more severe infections need to be treated with tablets or medicine taken by mouth, aciclovir bp 400mg.
You can take aciclovir either with or without food. Dosage in the paediatric population: Viral infections in adults and children Also called Available as Tablets, dispersible tablets, and oral liquid medicine Aciclovir is used to treat two common viral infections - varicella-zoster and herpes simplex. Patients who experience difficulty in swallowing the tablets may disperse them 400mg a minimum of 50ml water which should be stirred aciclovir drinking, aciclovir bp 400mg. Do not throw away any medicines via wastewater or household waste. Buy cialis 20mg aged 6 years and over should be given mg four times daily. If you experience difficulty in swallowing the mg or mg tablets they may be dispersed in a glass of water at least 50ml which should be stirred before drinking. Make sure you are not affected before you drive aciclovir operate machinery. By reporting side effects 400mg can help provide more information on the safety of this medicine. Drug information contained herein may be time sensitive, aciclovir bp 400mg. Accidental, repeated overdoses of oral aciclovir over several days have been associated with gastrointestinal effects eg nausea and vomiting and neurological effects eg headache and confusion. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse, aciclovir bp 400mg.
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