Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. Consult your doctor for more details.
How to use Zocor Take this medication by mouth as directed by your doctor, usually once daily in the evening. If you are using the tablet form of this medication, you may take this medication with or without food.
If you are using the liquid form of this medication, take this medication on an empty stomach. Simvastatin is also used to lower the risk of stroke , heart attack , and other heart complications in people with diabetes , coronary heart disease , or other risk factors Simvastatin is used in adults and children who are at least 10 years old.
Simvastatin may also be used for purposes not listed in this medication guide. Get emergency medical help if you have any of these signs of an allergic reaction: Stop using simvastatin and call your doctor at once if you have: Less serious side effects may include: On rare occasions, these muscle problems can be serious, including muscle breakdown resulting in kidney damage. If you get the following rare side effects, see a doctor straight away: Rare side effects may affect up to 1 in people: This is more likely if you have high levels of sugars and fats in your blood, are overweight and have high blood pressure.
Your doctor will monitor you while you are taking this medicine. Elevations in some laboratory blood tests of liver function and a muscle enzyme creatine kinase have been observed.
Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via Yellow card Scheme at: By reporting side effects you can help provide more information on the safety of this medicine. How to store Simvastatin Keep this medicine out of the sight and reach of children. Do not use the tablets after the expiry date stated on the label [EXP].
The expiry date refers to the last day of that month. Store the tablets in the original package. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment. Zocor has been shown to reduce both normal and elevated LDL-C concentrations.
Apolipoprotein B also falls substantially during treatment with Zocor. The reduction in non-vascular deaths did not reach statistical significance. The proportional reduction in event rate was similar in each subgroup of patients studied, including those without coronary disease but who had cerebrovascular or peripheral artery disease, men and women, those aged either under or over 70 years at entry into the study, presence or absence of hypertension, and notably those with LDL cholesterol below 3.
There was no statistically significant difference between groups in non-cardiovascular mortality. The absolute difference in LDL-C between the two groups over the course of the study was 0.
The safety profiles were similar between the two treatment groups except that the incidence of myopathy was approximately 1. Approximately half of these myopathy cases occurred during the first year of treatment.
The incidence of myopathy during each subsequent year of treatment was approximately 0. Paediatric population In a double-blind, placebo-controlled study, patients 99 boys Tanner Stage II and above and 76 girls who were at least one year post-menarche years of age mean age Pregnancy and breast-feeding Do not take ZOCOR if you are pregnant, trying to get pregnant or think you may be pregnant.
Do not take ZOCOR if you are breast-feeding, because it is not known if the medicine is passed into breast milk.
Ask your doctor or pharmacist for advice before taking any medicine. Driving and using machines ZOCOR is not expected to interfere with your ability to drive or to use machinery. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
If ZOCOR is effective during pregnancy or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus, 5mg zocor effective. Crestor is another option most effective, fewest side effects5mg zocor effective, but will not zocor generic for a while. Animal reproduction studies 5mg simvastatin in rats and rabbits showed no evidence of teratogenicity. You should check with your doctor or pharmacist if you are not sure. In 5mg with SLCO1B1 polymorphism there is a risk of increased exposure of simvastatin acid, 5mg zocor effective, which may lead to an increased risk of rhabdomyolysis see section 4. Zocor particular, tell your doctor or pharmacist if you are taking any of the following medicines: Do not use a household spoon because you may not get the correct dose. If you are using the liquid form of this medication, take this medication on an effective stomach. Patients treated with simvastatin had an adverse reaction profile similar to that of patients treated with placebo.
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