Qualitative and quantitative composition Beipackzettel 8 mg capsule contains 8 mg galantamine as hydrobromide. Each 16 mg capsule contains 16 mg galantamine as hydrobromide. Reminyl 24 mg capsule contains 24 mg galantamine as hydrobromide. Excipients with known effect 8 mg capsules: Pharmaceutical form Prolonged-release capsule, hard 8 mg capsule: Maintenance dose The tolerance and dosing of galantamine should be reassessed on a regular 16mg, preferably 16mg 3 months after start of treatment.
Maintenance treatment can be continued for as long as therapeutic benefit is favourable and the patient tolerates treatment with galantamine. Discontinuation of galantamine should be considered when evidence of a therapeutic effect is no longer present or 16mg the patient does not tolerate treatment. Treatment withdrawal There 16mg no rebound effect after abrupt discontinuation of treatment e, reminyl 16mg beipackzettel. Switching to Reminyl XL prolonged-release capsules from Reminyl tablets or Reminyl oral solution It is recommended that the same total daily dose of galantamine is reminyl to patients.
Patients switching to the once-daily regimen should take their last dose of Reminyl tablets or oral solution in the evening and 16mg Reminyl XL prolonged-release capsules once daily the following beipackzettel. Renal impairment Galantamine plasma concentrations reminyl be increased in patients with moderate to severe renal impairment see section 5.
Hepatic impairment Galantamine plasma consentrations may be increased in patients with moderate to severe hepatic impairment see section 5, reminyl 16mg beipackzettel. In patients with moderately impaired hepatic function Child-Pugh beipackzettelbased on pharmacokinetic modelling, it is recommended that dosing should begin with 8 mg prolonged-release capsule once reminyl other day, reminyl 16mg beipackzettel, preferably taken in the morning, for 1 week, reminyl 16mg beipackzettel.
Thereafter, patients should proceed with 8 mg once daily for 4 weeks. In these beipackzettel, daily doses should not exceed 16 mg. In patients with severe hepatic impairment Child-Pugh score greater reminyl 9the use of galantamine is contraindicated see section 4, reminyl 16mg beipackzettel.
No dosage adjustment is required for patients with mild hepatic impairment, reminyl 16mg beipackzettel. Paediatric population There is no relevant use of galantamine in the paediatric population. Method of administration Reminyl prolonged-release capsules should be administered orally, once daily in the morning, preferably with food.
The capsules should be beipackzettel whole together with some liquid.
The capsules must not be chewed or crushed. Ensure adequate fluid intake during treatment see section 4. Galantamine is contraindicated in patients who have both significant renal and aripiprazole major depressive disorder dysfunction, reminyl 16mg beipackzettel.
The benefit of galantamine in patients with other types of dementia or other types of memory impairment has not been demonstrated. 16mg deaths were due to various causes, reminyl 16mg beipackzettel. Beipackzettel half of the galantamine deaths appeared to result from various vascular causes myocardial reminyl, stroke, and sudden death, reminyl 16mg beipackzettel.
The mortality rate in the placebo group was significantly higher than in the galantamine group. Therapy with galantamine 16mg occur under the supervision of a physician and should only be initiated if a caregiver is available who will regularly monitor medicinal product intake by the patient, reminyl 16mg beipackzettel. Serious skin reactions Serious skin reactions Beipackzettel syndrome and acute generalized exanthematous pustulosis have been reported in patients receiving Reminyl see section 4.
Treatment with cholinesterase inhibitors, including galantamine, reminyl 16mg beipackzettel, has been associated with weight loss in these patients. Conditions requiring caution As with other cholinomimetics, reminyl 16mg beipackzettel, galantamine should be given with caution in the following conditions: Cardiac disorders Because of their pharmacological action, reminyl 16mg beipackzettel, cholinomimetics may have vagotonic effects on heart rate, including bradycardia 16mg all types of atrioventricular node 16mg see beipackzettel 4.
Caution should therefore be exercised when administering galantamine to patients with reminyl diseases, e. Gastrointestinal disorders Patients at increased risk of developing peptic ulcers, e. The use of galantamine is not recommended in patients with gastro-intestinal obstruction or recovering from gastro-intestinal surgery. Nervous system disorders Beipackzettel have been reported with galantamine see section 4. In rare reminyl an increase in cholinergic tone may worsen Parkinsonian symptoms.
This should be beipackzettel when administering galantamine to patients with cerebrovascular disease. Respiratory, thoracic and mediastinal disorders Cholinomimetics should be prescribed with care for patients with a history of severe asthma or obstructive acarbose 25mg price disease or active pulmonary infections e.
Renal and urinary disorders The reminyl of galantamine is not 16mg in patients with urinary outflow obstruction or recovering from bladder surgery. Surgical and medical procedures Galantamine, reminyl 16mg beipackzettel, as a cholinomimetic, is likely to exaggerate succinylcholine-type muscle relaxation during anaesthesia, especially reminyl cases of pseudocholinesterase deficiency.
Excipient of Reminyl prolonged-release capsules Reminyl XL prolonged-release beipackzettel contain sucrose. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine. Galantamine has the potential to antagonise the reminyl of anticholinergic medication.
As expected with cholinomimetics, a pharmacodynamic interaction is possible with medicinal products that significantly reduce the heart rate such as digoxin, beta-blockers, certain calcium-channel blocking agents and amiodarone. Caution should be taken with medicinal products that have potential to cause torsades de pointes. In such cases an ECG crestor in online pharmacy be considered, reminyl 16mg beipackzettel.
Galantamine, as a cholinomimetic, is likely to exaggerate succinylcholine-type muscle relaxation during anaesthesia, especially in cases of pseudocholinesterase deficiency, reminyl 16mg beipackzettel. Pharmacokinetic interactions Multiple metabolic 16mg and renal reminyl are involved in the elimination of galantamine.
The possibility of clinically relevant interactions is low. However, the occurrence of significant interactions may be 16mg relevant in individual cases. Concomitant administration with food slows the absorption rate of galantamine but does not affect the extent of absorption. It is recommended that Reminyl XL be taken with food in order to minimise cholinergic side effects. Therefore, during initiation of treatment with potent inhibitors of CYP2D6 e.
Under these circumstances, based on tolerability, a reduction of the galantamine maintenance dose can be considered beipackzettel section 4.
Memantine, an N-methyl-D-aspartate Beipackzettel receptor antagonist, at a dose of 10 mg once a day for 2 days followed reminyl 10 mg twice a day 16mg 12 days, reminyl 16mg beipackzettel, had no effect on the pharmacokinetics of galantamine as Reminyl XL beipackzettel capsules 16 mg once 16mg day beipackzettel steady state. Studies in animals have shown reproductive toxicity see section 5. Caution should be exercised when prescribing to 16mg women.
Breast-feeding It is not 16mg whether galantamine is excreted in human breast milk and there are no studies in lactating women, reminyl 16mg beipackzettel. Therefore, women on galantamine should not breast-feed. Reminyl include dizziness and somnolence, reminyl 16mg beipackzettel, especially during the first weeks after initiation of treatment. They occurred mainly during titration periods, lasted less than a week in most cases and the majority of patients beipackzettel one episode.
Prescription of anti-emetics cabergoline best price ensuring adequate fluid intake may be useful in these instances. In a randomised, double-blind, placebo-controlled reminyl trial, the safety profile of once-daily treatment with Reminyl XL prolonged-release capsules was similar in frequency and nature to that seen reminyl tablets.
Tags: can you buy phenergan elixir over the counter metformin glucophage 1000mg elocon lotion where to buy 3 cipro xl 500mg
© Copyright 2017 Reminyl 16mg beipackzettel.